First was an engaging conversation with Dean Buonomano on time in neuroscience and integrated information theory on the Brain Inspired podcast https://www.youtube.com/watch?v=KtR1-bmZXpA (2/6) #neuroscience
First was an engaging conversation with Dean Buonomano on time in neuroscience and integrated information theory on the Brain Inspired podcast https://www.youtube.com/watch?v=KtR1-bmZXpA (2/6) #neuroscience
Oscillatory control over representational geometry of sequence working memory in macaque frontal cortex
https://www.cell.com/current-biology/abstract/S0960-9822(25)00194-0
#neuroscience
Our research is now supported by a 2024 Simons Foundation Autism Research Initiative (SFARI) Pilot Award, co-funded by the Nancy Lurie Marks Family Foundation (NLMFF). I am grateful to both SFARI and NLMFF for investing in high-risk, high-reward science to advance understanding of autism spectrum disorders (ASD) and neurodevelopmental disorders.
The project will explore how mutations in chromatin regulators ASH1L and SETBP1 impair their crucial role in guiding the development of GABAergic neurons—key cells maintaining the brain’s balance between excitation and inhibition. Disruptions in this process are strongly linked to ASD, but the molecular pathways remain poorly understood.
By integrating genomic, proteomic, and functional approaches, we aim to reveal how these enzymes regulate gene activity during inhibitory neuron development and how their dysfunction contributes to ASD.
Official announcements:
SFARI: https://www.sfari.org/2025/04/08/announcing-the-recipients-of-the-2024-pilot-and-pilot-progression-awards/
NLMFF: https://www.nlmfoundation.org/grant/epigenetic-regulators-ash1l-and-setbp1-in-gabaergic-neuron-development-and-asd/
Latest from Kathy Nagel's lab:
"Inhibitory control explains locomotor statistics in walking Drosophila", Gattuso et al. 2025
https://www.pnas.org/doi/abs/10.1073/pnas.2407626122
"we measure and analyze trajectories evoked by attractive odor in walking Drosophila and develop a biologically plausible computational model of trajectory generation and modulation by sensory input. Our model provides a link between neural architectures and locomotor behavior and highlights the potential role of inhibition in shaping the curvature and speed of trajectories. Inspired by this model, we experimentally identify single neurons and populations that modulate either curvature or speed in the manner predicted by our model."
#Consciousness #Neuroscience #thalamus
"A team of scientists has identified areas of the brain that are activated when a person becomes aware of themself and their thoughts."
Scientists Think They’ve Found the Region of the Brain That Regulates Conscious Perception
"A new experiment suggests that the thalamus plays a key role in humans becoming consciously aware of stimuli their brain receives."
https://www.wired.com/story/scientists-think-theyve-found-the-brain-region-that-regulates-conscious-perception/
Imagine controlling machines with only your thoughts! Brain-Computer Interfaces (BCIs) are turning stuff of sci-fi into reality, and Mouser Electronics is leading the way.
Mouser has great content about this tech on their Empowering Innovation Together platform.
Check out mouser.com/empowering-innovation to see how their tech is shaping the future.
Thank you to Mouser Electronics for sponsoring Embedded.
New paper!
Cognitive independence and interactions between cerebral hemispheres
https://doi.org/10.1016/j.neuropsychologia.2025.109153
#neuroscience
A team from the Laboratory for Soft Bioelectronic Interfaces has developed a flexible auditory brainstem implant (ABI) that closely conforms to the curved surface of the brainstem. The technology has successfully demonstrated high-resolution “prosthetic hearing” in macaques.
https://www.europesays.com/uk/39495/ Early Alzheimer’s Clues Found in Adults as Young as 24 #Aging #Alzheimer'sDisease #BrainResearch #cognition #ColumbiaUniversity #Genetics #Health #neurobiology #Neurology #Neuroscience #UK #UnitedKingdom
Feedback isn’t about speed — it’s about impact.
Neuroscience shows that waiting up to 48 hours can turn a tough conversation into real growth.
New article just dropped
https://avelino.run/the-power-of-two-days-neuroscience-behind-the-48-hour-rule-for-effective-feedback/
#Leadership #Neuroscience #Feedback #PeopleManagement
Key Parkinson's Protein Structure And Malfunction Revealed For First Time
#science #biology #neuroscience
https://www.sciencealert.com/key-parkinsons-protein-structure-and-malfunction-revealed-for-first-time
A 20-minute game of Tetris reduced traumatic memories in pandemic frontline workers
Scientists have just made a massive leap in neuroscience—creating an incredibly accurate digital twin of the human brain. This breakthrough could revolutionize how we treat neurological diseases, understand consciousness, and even explore the mind-machine interface. The future of brain science just got a lot more exciting!
#GoodNews #Neuroscience #BrainTech #DigitalTwin #FutureOfMedicine #AI #Innovation
https://thedebrief.org/the-holy-grail-of-neuroscience-researchers-create-stunningly-accurate-digital-twin-of-the-brain/
New results!
Evidence for an active handoff between cerebral hemispheres during target tracking
https://www.biorxiv.org/content/10.1101/2025.04.18.649553v1
#neuroscience
When retinal cells go rogue in albino mice, their misdirected connections reveal an unexpected way the brain's wiring adapts. This study sheds light on how spontaneous neural activity shapes synaptic development. #Neuroscience
https://elifesciences.org/articles/100990?utm_source=mastodon&utm_medium=social&utm_campaign=organic
What did dopamine do to deserve this?
A guest post I did for tommy Blanchard's Cognitive Wonderland blog, about the surreal vilification of a vital neurotransmitter, and how this is having negative consequences for us all.
@pdbrooker I'm super interested to see where this takes you. How we construct meaning around multi-sensory experiences, and how our interaction with sound changes when we're experiencing ourselves making sounds, making sounds with others, etc. I think people in the #neuroscience field would have a research question ideas that could excite you for future interdisciplinary research projects on how your tools affect the way brains react to seeing + hearing + feeling + all at the same time.