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#transplants

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Once again a story about child organ transplants is both heart-breaking & heart-warming at the same time...

The children and parents on both sides of these stories deserve our support.

I don't have any smart comment here, just awe at the emotional and medical fortitude fo all involved.... from tragedy comes hope.

#transplants #children

theguardian.com/society/2024/d

The Guardian · ‘Selfless parents gave their child’s organs to save my son. I’m in awe of them’By James Tapper

The health ministry is overhauling its organ transplant system to enable high-priority patients to register with multiple hospitals for such surgeries to avoid missing out on transplants as a result of logistical issues at individual facilities. japantimes.co.jp/news/2024/12/ #japan #sciencehealth #health #transplants #hospitals

The Japan Times · Multi-facility option set for patients awaiting organ transplantsBy The Japan Times

Japanese startup PorMedTec announced Monday that it has successfully transplanted a genetically engineered pig kidney into a crab‐eating macaque, a first in Japan that is hoped will provide insights into the future use of animal kidneys in humans. japantimes.co.jp/news/2024/11/ #japan #sciencehealth #transplants #hospitals #health #medicine

The Japan Times · Startup transplants pig kidney into monkey for first time in JapanBy Tomoko Otake

Two Decades of Advances and Limitations in Organ Recellularization

mdpi.com/1467-3045/46/8/543

MDPITwo Decades of Advances and Limitations in Organ RecellularizationThe recellularization of tissues after decellularization is a relatively new technology in the field of tissue engineering (TE). Decellularization involves removing cells from a tissue or organ, leaving only the extracellular matrix (ECM). This can then be recellularized with new cells to create functional tissues or organs. The first significant mention of recellularization in decellularized tissues can be traced to research conducted in the early 2000s. One of the landmark studies in this field was published in 2008 by Ott, where researchers demonstrated the recellularization of a decellularized rat heart with cardiac cells, resulting in a functional organ capable of contraction. Since then, other important studies have been published. These studies paved the way for the widespread application of recellularization in TE, demonstrating the potential of decellularized ECM to serve as a scaffold for regenerating functional tissues. Thus, although the concept of recellularization was initially explored in previous decades, these studies from the 2000s marked a major turning point in the development and practical application of the technology for the recellularization of decellularized tissues. The article reviews the historical advances and limitations in organ recellularization in TE over the last two decades.

Kyoto University Hospital is looking to develop a treatment for severe Type 1 diabetes using induced pluripotent stem cells reprogrammed to function as pancreatic islet cells, which produce the hormones that regulate glucose levels in the blood. japantimes.co.jp/news/2024/09/ #japan #sciencehealth #kyotouniversity #kyotouniversityhospital #ips #transplants #medicine

The Japan Times · Kyoto University Hospital seeks to treat Type 1 diabetes using iPS cellsBy Tomoko Otake