PLOS Biology<p>The flight response in <a href="https://fediscience.org/tags/worms" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>worms</span></a> comes at a cost. This study defines a brain-gut pathway mediating this adaptive tradeoff, wherein <a href="https://fediscience.org/tags/tyramine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>tyramine</span></a> stimulates INS-3 expression in the intestine, leading to systemic activation of <a href="https://fediscience.org/tags/insulin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>insulin</span></a> signaling &amp; reduced stress resistance <a href="https://fediscience.org/tags/plosbiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>plosbiology</span></a> <a href="https://plos.io/42Ek3Lz" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="">plos.io/42Ek3Lz</span><span class="invisible"></span></a></p>