I'm not an animator, but since I can use UE to do it now and not have to try to exhume my Blender knowledge that is always completely withered by the time I use it once every 6 months, I'm having a go.
Chug, chug, chug!
There we go, not bad for a quick job by a non-animator I think The idea is the material will change on the potion as he drinks, and at the end he's chucking the empty bottle over his shoulder so it'll detach and smash somewhere, the cheeky littering bastard