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#mechanics

9 posts5 participants0 posts today
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Rxiv mechanobio

📰 "Equilibrium Conserving Neural Operators for Super-Resolution Learning"
arxiv.org/abs/2504.13422 #Physics.Comp-Ph #Mechanics #Matrix #Cs.Lg

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arXiv.orgEquilibrium Conserving Neural Operators for Super-Resolution LearningNeural surrogate solvers can estimate solutions to partial differential equations in physical problems more efficiently than standard numerical methods, but require extensive high-resolution training data. In this paper, we break this limitation; we introduce a framework for super-resolution learning in solid mechanics problems. Our approach allows one to train a high-resolution neural network using only low-resolution data. Our Equilibrium Conserving Operator (ECO) architecture embeds known physics directly into the network to make up for missing high-resolution information during training. We evaluate this ECO-based super-resolution framework that strongly enforces conservation-laws in the predicted solutions on two working examples: embedded pores in a homogenized matrix and randomly textured polycrystalline materials. ECO eliminates the reliance on high-fidelity data and reduces the upfront cost of data collection by two orders of magnitude, offering a robust pathway for resource-efficient surrogate modeling in materials modeling. ECO is readily generalizable to other physics-based problems.
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Rxiv mechanobio

📰 "Structure and function of vimentin in the generation and secretion of extracellular vimentin in response to inflammation"
doi.org/doi:10.1186/s12964-025
pubmed.ncbi.nlm.nih.gov/402515
#Mechanics #Vimentin

BioMed CentralStructure and function of vimentin in the generation and secretion of extracellular vimentin in response to inflammation - Cell Communication and SignalingThe canonical functions of vimentin in cell mechanics and migration have been recently expanded by the discovery of new roles for extracellular vimentin (ECV) in immune responses to infection, injury and cancer. In contrast with the predominantly filamentous form of intracellular vimentin, ECV exists largely as soluble oligomers. The release of ECV from intact cells is dependent on mechanisms that regulate the assembly and disassembly of intracellular vimentin, which are influenced by discrete post-translational modifications. In this review we highlight the processes that promote the conversion of intracellular and insoluble vimentin filaments to ECV and secretion mechanisms. Insights into the regulation of ECV release from stromal and immune cells could provide new diagnostic and therapeutic approaches for assessing and controlling inflammatory diseases.
Public
CyanCqueak

My son pulled out a textbook at his tutoring centre and asked me to do this question.

Moving past the odd statement that the object is at rest when the forces aren't balanced, when I resolve the weight of the I get a net force along the slope of 2N, assuming a friction coefficient of 0.

The friction coefficient would need to be greater than 1 for the object to be at rest with the initial applied forces.

Textbook says the answer is 0. Am I missing something? #maths #mechanics

Public
Rxiv mechanobio

📰 "Retinotopic Mechanics derived using classical physics"
arxiv.org/abs/2109.11632 #Physics.Bio-Ph #Mechanics #Q-Bio.Nc #Dynamics #Cell

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arXiv.orgRetinotopic Mechanics derived using classical physicsThe concept of a cell$'$s receptive field is a bedrock in systems neuroscience, and the classical static description of the receptive field has had enormous success in explaining the fundamental mechanisms underlying visual processing. Borne out by the spatio-temporal dynamics of visual sensitivity to probe stimuli in primates, I build on top of this static account with the introduction of a new computational field of research, retinotopic mechanics. At its core, retinotopic mechanics assumes that during active sensing receptive fields are not static but can shift beyond their classical extent. Specifically, the canonical computations and the neural architecture that supports these computations are inherently mediated by a neurobiologically inspired force field (e.g.,$R_s\propto \sim 1 /ΔM$). For example, when the retina is displaced because of a saccadic eye movement from one point in space to another, cells across retinotopic brain areas are tasked with discounting the retinal disruptions such active surveillance inherently introduces. This neural phenomenon is known as spatial constancy. Using retinotopic mechanics, I propose that to achieve spatial constancy or any active visually mediated task, retinotopic cells, namely their receptive fields, are constrained by eccentricity dependent elastic fields. I propose that elastic fields are self-generated by the visual system and allow receptive fields the ability to predictively shift beyond their classical extent to future post-saccadic location such that neural sensitivity which would otherwise support intermediate eccentric locations likely to contain retinal disruptions is transiently blunted.
Public
Rxiv mechanobio

📰 "Retinotopic Mechanics derived using classical physics"
arxiv.org/abs/2109.11632 #Physics.Bio-Ph #Mechanics #Q-Bio.Nc #Dynamics #Cell

arXiv logo
arXiv.orgRetinotopic Mechanics derived using classical physicsThe concept of a cell$'$s receptive field is a bedrock in systems neuroscience, and the classical static description of the receptive field has had enormous success in explaining the fundamental mechanisms underlying visual processing. Borne out by the spatio-temporal dynamics of visual sensitivity to probe stimuli in primates, I build on top of this static account with the introduction of a new computational field of research, retinotopic mechanics. At its core, retinotopic mechanics assumes that during active sensing receptive fields are not static but can shift beyond their classical extent. Specifically, the canonical computations and the neural architecture that supports these computations are inherently mediated by a neurobiologically inspired force field (e.g.,$R_s\propto \sim 1 /ΔM$). For example, when the retina is displaced because of a saccadic eye movement from one point in space to another, cells across retinotopic brain areas are tasked with discounting the retinal disruptions such active surveillance inherently introduces. This neural phenomenon is known as spatial constancy. Using retinotopic mechanics, I propose that to achieve spatial constancy or any active visually mediated task, retinotopic cells, namely their receptive fields, are constrained by eccentricity dependent elastic fields. I propose that elastic fields are self-generated by the visual system and allow receptive fields the ability to predictively shift beyond their classical extent to future post-saccadic location such that neural sensitivity which would otherwise support intermediate eccentric locations likely to contain retinal disruptions is transiently blunted.
Public
Rxiv mechanobio

📰 "Extending the QMM Framework to the Strong and Weak Interactions"
arxiv.org/abs/2504.03817 #Physics.Gen-Ph #Mechanics #Matrix

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arXiv.orgExtending the QMM Framework to the Strong and Weak InteractionsWe extend the Quantum Memory Matrix (QMM) framework, originally developed to reconcile quantum mechanics and general relativity by treating space-time as a dynamic information reservoir, to incorporate the full suite of Standard Model gauge interactions. In this discretized, Planck-scale formulation, each space-time cell possesses a finite-dimensional Hilbert space that acts as a local memory, or quantum imprint, for matter and gauge field configurations. We focus on embedding non-Abelian SU(3)c (quantum chromodynamics) and SU(2)L x U(1)Y (electroweak interactions) into QMM by constructing gauge-invariant imprint operators for quarks, gluons, electroweak bosons, and the Higgs mechanism. This unified approach naturally enforces unitarity by allowing black hole horizons, or any high-curvature region, to store and later retrieve quantum information about color and electroweak charges, thereby preserving subtle non-thermal correlations in evaporation processes. Moreover, the discretized nature of QMM imposes a Planck-scale cutoff, potentially taming UV divergences and modifying running couplings at trans-Planckian energies. We outline major challenges, such as the precise formulation of non-Abelian imprint operators and the integration of QMM with loop quantum gravity, as well as possible observational strategies - ranging from rare decay channels to primordial black hole evaporation spectra - that could provide indirect probes of this discrete, memory-based view of quantum gravity and the Standard Model.
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